| NCAAF | 11/22 00:30 | 1 |
[83] Eastern Michigan
v
Buffalo
[122] 
|
L | 24-11 | |
| NCAAF | 11/16 00:00 | 1 |
[6] Buffalo
v
Miami Ohio
[2] |
L | 10-23 | |
| NCAAF | 11/08 00:30 | 1 |
[5] Ohio
v
Buffalo
[3]
|
L | 20-10 | |
| NCAAF | 10/31 23:30 | 1 |
[3] Buffalo
v
Toledo
[1] 
|
L | 13-31 | |
| NCAAF | 10/21 19:30 | 1 |
[3] Buffalo
v
Kent State
[10] 
|
W | 24-6 | |
| NCAAF | 10/14 19:30 | 1 |
[12] Bowling Green
v
Buffalo
[2]
|
L | 24-14 | |
| NCAAF | 10/07 18:00 | 1 |
[5] Central Michigan
v
Buffalo
[3]
|
W | 13-37 | |
| NCAAF | 09/30 16:00 | 1 |
[4] Buffalo
v
Akron
[7] 
|
W | 13-10 | |
| NCAAF | 09/23 23:30 | 1 |
[4] Buffalo
v
UL Lafayette
[16] |
L | 38-45 | |
| NCAAF | 09/16 16:00 | 1 |
[41] Libertay
v
Buffalo
[121]
|
L | 55-27 | |
| NCAAF | 09/09 22:00 | 1 |
[51] Fordham
v
Buffalo
[114]
|
L | 40-37 | |
| NCAAF | 09/02 19:30 | 1 |
[24] Buffalo
v
Wisconsin
[24] 
|
L | 17-38 | |
| NCAAF Bowl Games | 12/27 17:00 | 304 |
[19] Georgia Southern
v
Buffalo
[19]
|
W | 21-23 | |
| NCAAF | 12/02 18:00 | 1 |
Akron
v
Buffalo
|
W | 22-23 | |
| NCAAF | 11/26 18:00 | 1 |
Kent State
v
Buffalo
|
L | 30-27 | |
| NCAAF | 11/19 20:30 | 1 |
Akron
v
Buffalo
|
- | Postponed | |
| NCAAF | 11/10 00:00 | 1 |
[1] Buffalo
v
Central Michigan
[12]
|
L | 27-31 | |
| NCAAF | 11/01 23:30 | 1 |
[1] Buffalo
v
Ohio
[11]
|
L | 24-45 | |
| NCAAF | 10/22 17:00 | 1 |
[3] Toledo
v
Buffalo
[1]
|
W | 27-34 | |
| NCAAF | 10/15 17:00 | 1 |
[1] Buffalo
v
Massachusetts
[127] |
W | 34-7 | |
| NCAAF | 10/08 16:00 | 1 |
[1] Buffalo
v
Bowling Green
[5]
|
W | 38-7 | |
| NCAAF | 10/01 19:30 | 1 |
[3] Miami Ohio
v
Buffalo
[1]
|
W | 20-24 | |
| NCAAF | 09/24 16:00 | 1 |
[3] Buffalo
v
Eastern Michigan
[9]
|
W | 50-31 | |
| NCAAF | 09/17 17:00 | 1 |
[3] Buffalo
v
Coastal Carolina
[5] 
|
L | 26-38 | |
| NCAAF | 09/10 22:00 | 1 |
[28] Holy Cross
v
Buffalo
[107]
|
L | 37-31 | |
| NCAAF | 09/03 16:00 | 1 |
[59] Buffalo
v
Maryland
[5] 
|
L | 10-31 | |
| NCAAF | 11/24 00:00 | 1 |
[98] Buffalo
v
Ball State
[83] 
|
L | 3-20 | |
| NCAAF | 11/18 00:00 | 1 |
[34] Northern Illinois
v
Buffalo
[89]
|
L | 33-27 | |
| NCAAF | 11/10 00:00 | 1 |
[83] Buffalo
v
Miami Ohio
[86] |
L | 18-45 | |
| NCAAF | 10/30 16:00 | 1 |
[117] Bowling Green
v
Buffalo
[80]
|
L | 56-44 |