| WTA - Dubai | 02/17 06:30 | 46 | [39] Veronika Kudermetova v Bethanie Mattek-Sands [389] | 6-4,6-2 | |
| WTA - Dubai | 02/16 09:05 | 45 | [81] Kirsten Flipkens v Bethanie Mattek-Sands [385] | 1-6,1-6 | |
| WTA - Dubai | 02/15 09:40 | 44 | [385] Bethanie Mattek-Sands v Ajla Tomljanovic [57] | 6-4,3-6,7-6 | |
| WTA - Houston | 11/15 16:00 | 26 | Irina Falconi v Bethanie Mattek-Sands | 6-1,6-3 | |
| WTA - Houston | 11/13 19:20 | 25 | [398] Bethanie Mattek-Sands v Allie Kiick [141] | 6-0,6-0 | |
| WTA - Houston | 11/11 21:05 | 24 | [191] Danielle Lao v Bethanie Mattek-Sands [398] | 3-6,4-6 | |
| WTA - Moskva | 10/12 12:05 | 45 | [405] Bethanie Mattek-Sands v Varvara Flink [135] | 2-6,3-6 | |
| WTA Wuhan | 09/21 05:45 | 46 | [65] Svetlana Kuznetsova v Bethanie Mattek-Sands [438] | 6-2,6-2 | |
| WTA Wuhan | 09/20 08:40 | 45 | [243] Fang Ying Xun v Bethanie Mattek-Sands [438] | 6-2,4-6,3-6 | |
| US Open - Kvinder | 08/20 18:35 | 44 | [436] Bethanie Mattek-Sands v Ana Bogdan [147] | 5-7,5-7 | |
| WTA - Cincinnati | 08/11 16:00 | 46 | [100] Astra Sharma v Bethanie Mattek-Sands [482] | 6-4,6-4 | |
| WTA - Cincinnati | 08/10 18:55 | 45 | [482] Bethanie Mattek-Sands v Elena Rybakina [63] | 6-3,6-2 | |
| WTA - San Jose | 08/01 02:00 | 26 | [29] Carla Suarez Navarro v Bethanie M Sands [78] | 3-6,6-1,6-2 | |
| WTA - San Jose | 07/31 02:00 | 25 | Venus Williams v Bethanie M Sands | 7-6,3-6,1-6 | |
| WTA - Bukarest | 07/15 17:55 | 25 | Bethanie Mattek-Sands v Ysaline Bonaventure | Cancelled | |
| Australian Open - Kvinder | 01/14 01:35 | 23 | [348] Bethanie Mattek-Sands v Zoe Hives [225] | 1-6,2-6 | |
| WTA - Sydney | 01/06 03:40 | 45 | [363] Bethanie Mattek-Sands v Monica Puig [53] | 6-3,2-6,2-6 | |
| WTA - Auckland | 12/31 02:00 | 25 | [53] Monica Puig v Bethanie Mattek-Sands [363] | 6-3,6-2 | |
| WTA Seoul | 09/18 04:20 | 25 | Bethanie Mattek-Sands v Agnieszka Radwanska | 4-6,5-7 | |
| US Open - Kvinder | 08/22 23:00 | 44 | Bethanie Mattek-Sands v Tereza Smitkova | 5-7,6-4,1-6 | |
| WTA - Cincinnati | 08/13 17:50 | 24 | Bethanie Mattek-Sands v Madison Keys | 6-3,6-7,4-6 | |
| WTA Montreal Qual | 08/04 22:35 | 44 | Kirsten Flipkens v Bethanie Mattek-Sands | 6-1,6-4 | |
| WTA - Washington | 07/31 18:30 | 25 | Bethanie Mattek-Sands v Sloane Stephens | 5-7,4-6 | |
| French Open - Kvinder | 05/31 11:55 | 24 | Bethanie Mattek-Sands v Andrea Petkovic | 0-6,6-7 | |
| French Open - Kvinder | 05/29 09:00 | 23 | Bethanie Mattek-Sands v Johanna Larsson | 6-4,6-3 | |
| WTA Rome Qual | 05/12 13:50 | 45 | Alison Van Uytvanck v Bethanie Mattek-Sands | 7-5,1-6,6-1 | |
| WTA Madrid Qual | 05/05 12:10 | 46 | Bethanie Mattek-Sands v Anna Karolina Schmiedlova | 6-4,2-6,5-7 | |
| WTA Madrid Qual | 05/04 15:00 | 45 | Bethanie Mattek-Sands v Caroline Dolehide | 4-6,7-6,6-1 | |
| WTA - Rabat | 05/01 18:15 | 25 | Bethanie Mattek-Sands v Su-Wei Hsieh | 6-3,6-7,1-6 | |
| WTA - Charleston | 04/02 19:15 | 24 | Aleksandra Krunic v Bethanie Mattek-Sands | 6-2,6-2 |