| NCAAF | 11/18 18:00 | 7 | Wheaton Thunder v Mount St. Joseph Lions | L | 41-34 | |
| NCAAF | 11/11 18:30 | 1 | Rose Hulman Engineers v Mount St. Joseph Lions | W | 20-68 | |
| NCAAF | 11/04 17:30 | 1 | Bluffton Beavers v Mount St. Joseph Lions | W | 27-49 | |
| NCAAF | 10/28 17:30 | 1 | Mount St. Joseph Lions v Franklin College Grizzlies | W | 55-0 | |
| NCAAF | 10/21 17:30 | 1 | Mount St. Joseph Lions v Hanover Panthers | W | 52-27 | |
| NCAAF | 10/14 17:30 | 1 | Mount St. Joseph Lions v Anderson Ravens | W | 77-14 | |
| NCAAF | 10/07 17:30 | 1 | Defiance Yellow Jackets v Mount St. Joseph Lions | W | 21-62 | |
| NCAAF | 09/30 17:30 | 1 | Mount St. Joseph Lions v Manchester Spartans | W | 69-14 | |
| NCAAF | 09/16 17:00 | 1 | Hope Flying Dutchmen v Mount St. Joseph Lions | L | 40-35 | |
| NCAAF | 09/09 16:00 | 1 | Mount St. Joseph Lions v Hiram Terriers | W | 62-21 | |
| NCAAF | 09/02 17:30 | 1 | Baldwin Wallace Yellow Jackets v Mount St. Joseph Lions | W | 33-46 | |
| NCAAF | 11/19 17:00 | 7 | Alma College Scots v Mount St. Joseph Lions | L | 41-21 |