Stadium: Cajun Field Round: 1
Home Manager: Michael Desormeaux Away Manager: Terry Bowden
| NCAAF | 2022/09/25 00:00 | Lafayette v UL Monroe | W | 17-21 |
| NCAAF | 2021/11/27 21:00 | UL Monroe v Lafayette | L | 16-21 |
| NCAAF | 2020/11/28 20:00 | Lafayette v UL Monroe | L | 70-20 |
| NCAAF | 2019/12/01 00:30 | UL Monroe v Lafayette | L | 30-31 |
| NCAAF | 2018/11/24 20:00 | Lafayette v UL Monroe | L | 31-28 |
| NCAAF | 2017/09/23 21:00 | UL Monroe v Lafayette | W | 56-50 |
| NCAAF | 2016/12/03 20:00 | Lafayette v UL Monroe | L | 30-3 |
| NCAAF | 2015/10/31 21:00 | Lafayette v UL Monroe | L | 30-24 |
| NCAAF | 2014/11/16 00:00 | UL Monroe v Lafayette | L | 27-34 |
| NCAAF | 2012/11/03 12:00 | UL Monroe v Lafayette | L | 24-40 |
| NCAAF | 2011/11/05 12:00 | Lafayette v UL Monroe | L | 36-35 |
| NCAAF | 2010/11/27 12:00 | UL Monroe v Lafayette | L | 22-23 |
| NCAAF | 2009/11/21 12:00 | Lafayette v UL Monroe | L | 21-17 |
| NCAAF | 2008/10/04 12:00 | UL Monroe v Lafayette | L | 35-44 |
| NCAAF | 2007/11/24 12:00 | Lafayette v UL Monroe | W | 11-17 |
| NCAAF | 2006/12/02 12:00 | Lafayette v UL Monroe | W | 20-39 |
| NCAAF | 2005/11/26 12:00 | UL Monroe v Lafayette | L | 21-54 |
| NCAAF | 2004/11/20 12:00 | UL Monroe v Lafayette | W | 13-10 |
| NCAAF | 2003/10/11 12:00 | Lafayette v UL Monroe | W | 42-45 |
| NCAAF | 2002/11/23 12:00 | UL Monroe v Lafayette | W | 34-10 |
| NCAAF | 2001/10/27 12:00 | Lafayette v UL Monroe | L | 17-12 |
| NCAAF | 2000/11/04 12:00 | UL Monroe v Lafayette | L | 18-21 |