[6] Boston River 2-0 Danubio [5] 2022-06-20 19:00
Stadium: Estadio Juan Antonio Lavalleja Round: 2
Referee: Javier Burgos Home Manager: Ignacio Ithurralde Away Manager: Jorge Daniel Fossati Lurachi
Head to Head
| Uruguay - Apertura | 2022/04/15 19:00 | Danubio v Boston River | D | 0-0 |
| Uruguay - Clausura | 2021/03/19 21:15 | Boston River v Danubio | L | 1-5 |
| Uruguay - Torneo Intermedio | 2020/11/11 16:30 | Danubio v Boston River | D | 0-0 |
| Uruguay - Apertura | 2020/09/20 16:00 | Danubio v Boston River | D | 2-2 |
| Uruguay - Clausura | 2019/12/05 20:00 | Boston River v Danubio | W | 3-1 |
| Uruguay - Torneo Intermedio | 2019/08/17 18:00 | Danubio v Boston River | W | 1-2 |
| Uruguay - Apertura | 2019/06/02 18:00 | Danubio v Boston River | L | 1-0 |
| Uruguay - Clausura | 2018/09/09 18:30 | Boston River v Danubio | D | 0-0 |
| Uruguay - Apertura | 2018/03/24 19:00 | Danubio v Boston River | D | 0-0 |
| Uruguay - Clausura | 2017/12/03 20:00 | Danubio v Boston River | L | 1-0 |
| Uruguay - Apertura | 2017/05/14 18:00 | Boston River v Danubio | L | 0-3 |
| Uruguay - Apertura | 2016/10/29 19:00 | Boston River v Danubio | L | 1-2 |