[90] Michigan State 24-39 Penn State [104] 2020-12-12 17:00
Stadium: Beaver Stadium Round: 1
Head to Head
| NCAAF | 2019/10/26 19:30 | Penn State v Michigan State | L | 28-7 |
| NCAAF | 2018/10/13 19:30 | Michigan State v Penn State | W | 21-17 |
| NCAAF | 2017/11/04 16:00 | Penn State v Michigan State | W | 24-27 |
| NCAAF | 2016/11/26 20:30 | Michigan State v Penn State | L | 12-45 |
| NCAAF | 2015/11/28 20:30 | Michigan State v Penn State | W | 55-16 |
| NCAAF | 2014/11/29 20:30 | Penn State v Michigan State | W | 10-34 |
| NCAAF | 2010/11/27 12:00 | Penn State v Michigan State | W | 22-28 |
| NCAAF | 2009/11/21 12:00 | Michigan State v Penn State | L | 14-42 |
| NCAAF | 2008/11/22 12:00 | Penn State v Michigan State | L | 49-18 |
| NCAAF | 2007/11/17 12:00 | Michigan State v Penn State | W | 35-31 |
| NCAAF | 2006/11/18 12:00 | Penn State v Michigan State | L | 17-13 |
| NCAAF | 2005/11/19 12:00 | Michigan State v Penn State | L | 22-31 |
| NCAAF | 2004/11/20 12:00 | Penn State v Michigan State | L | 37-13 |
| NCAAF | 2003/11/22 12:00 | Michigan State v Penn State | W | 41-10 |
| NCAAF | 2002/11/23 12:00 | Penn State v Michigan State | L | 61-7 |
| NCAAF | 2001/11/24 12:00 | Michigan State v Penn State | L | 37-42 |
| NCAAF | 2000/11/18 12:00 | Penn State v Michigan State | L | 42-23 |