Stadium: Saluki Stadium Round: 1
Home Manager: Nick Hill Away Manager: Curt Mallory
| NCAAF | 2018/10/13 19:00 | SO Illinois v Illinois State | L | 3-51 |
| NCAAF | 2018/10/06 22:00 | SO Illinois v Youngstown State | L | 14-17 |
| NCAAF | 2018/09/29 23:00 | South Dakota v SO Illinois | L | 31-24 |
| NCAAF | 2018/09/15 23:00 | SE Missouri St v SO Illinois | L | 48-44 |
| NCAAF | 2018/09/08 20:00 | SO Illinois v Mississippi | L | 41-76 |
| NCAAF | 2018/08/30 23:00 | SO Illinois v Murray State | W | 49-10 |
| NCAAF | 2017/11/18 19:00 | Western Illinois v SO Illinois | L | 28-14 |
| NCAAF | 2017/11/11 19:00 | SO Illinois v Youngstown State | L | 20-28 |
| NCAAF | 2018/10/13 18:00 | Missouri St v Indiana State | L | 29-26 |
| NCAAF | 2018/10/06 23:00 | Indiana State v South Dakota State | L | 51-54 |
| NCAAF | 2018/09/27 23:00 | Northern Iowa v Indiana State | L | 33-0 |
| NCAAF | 2018/09/15 23:00 | Indiana State v Eastern Illinois | W | 55-41 |
| NCAAF | 2018/09/08 23:00 | Indiana State v Louisville | L | 7-31 |
| NCAAF | 2018/08/30 23:00 | Indiana State v Quincy | W | 49-0 |
| NCAAF | 2017/11/18 22:00 | Northern Iowa v Indiana State | L | 41-3 |
| NCAAF | 2017/11/11 18:00 | Indiana State v Western Illinois | L | 0-45 |