Stadium: Nissan Stadium Round: 1
| NCAAF | 2021/09/25 19:00 | Tennessee State v SE Missouri St | W | 14-47 |
| NCAAF | 2021/04/11 19:30 | SE Missouri St v Tennessee State | W | 46-23 |
| NCAAF | 2019/11/02 19:00 | SE Missouri St v Tennessee State | W | 32-13 |
| NCAAF FCS | 2018/11/03 18:00 | Tennessee State v SE Missouri St | W | 21-38 |
| NCAAF | 2017/11/11 20:00 | Tennessee State v SE Missouri St | L | 23-20 |
| NCAAF | 2022/10/29 18:00 | Eastern Kentucky v SE Missouri St | L | 28-23 |
| NCAAF | 2022/10/22 18:00 | SE Missouri St v Northwestern State | W | 51-16 |
| NCAAF | 2022/10/08 19:00 | Tennessee Tech v SE Missouri St | W | 20-34 |
| NCAAF | 2022/10/01 18:00 | SE Missouri St v Lindenwood | W | 49-28 |
| NCAAF | 2022/09/24 19:00 | Central Arkansas v SE Missouri St | W | 27-35 |
| NCAAF | 2022/09/17 19:00 | Nicholls State v SE Missouri St | W | 16-42 |
| NCAAF | 2022/09/10 23:00 | SE Missouri St v SO Illinois | W | 34-31 |
| NCAAF | 2022/09/03 18:00 | SE Missouri St v Iowa State | L | 10-42 |
| NCAAF | 2022/10/29 19:00 | Tennessee State v Murray State | L | 3-19 |
| NCAAF | 2022/10/22 19:00 | Eastern Illinois v Tennessee State | W | 17-37 |
| NCAAF | 2022/10/15 23:00 | Tennessee State v Tennessee Tech | W | 30-14 |
| NCAAF | 2022/10/08 22:00 | Bethune Cookman v Tennessee State | W | 17-41 |
| NCAAF | 2022/10/01 18:00 | Tennessee State v Lane College Dragons | L | 27-28 |
| NCAAF | 2022/09/17 23:00 | Tennessee State v Middle Tennessee St. | L | 6-49 |
| NCAAF | 2022/09/10 23:00 | Jackson State v Tennessee State | L | 16-3 |
| NCAAF | 2022/09/03 20:00 | Tennessee State v East Washington | L | 29-36 |