[115] Howard 20-42 South Florida [112] 2022-09-10 23:00
Stadium: Raymond James Stadium Round: 1
Home Manager: Jeff Scott Away Manager: Larry Scott
Home History
| NCAAF | 2022/09/03 22:00 | Howard v Hampton | L | 28-31 |
| NCAAF | 2021/11/13 18:00 | North Carolina Central v Howard | L | 45-27 |
| NCAAF | 2021/11/06 18:00 | Howard v South Carolina State | L | 12-15 |
| NCAAF | 2021/10/30 18:00 | Howard v Delaware State | L | 23-30 |
| NCAAF | 2021/10/23 17:00 | Norfolk State v Howard | L | 45-31 |
| NCAAF | 2021/10/09 00:00 | Morgan State v Howard | W | 0-27 |
| NCAAF | 2021/10/02 17:00 | Sacred Heart v Howard | W | 17-22 |
| NCAAF | 2021/09/25 16:00 | Howard v Robert Morris | L | 16-22 |
Away History
| NCAAF | 2022/09/03 20:00 | BYU v South Florida | L | 50-21 |
| NCAAF | 2021/11/26 20:30 | South Florida v Central Florida | L | 13-17 |
| NCAAF | 2021/11/20 17:00 | South Florida v Tulane | L | 14-45 |
| NCAAF | 2021/11/12 23:00 | Cincinnati v South Florida | L | 45-28 |
| NCAAF | 2021/11/06 23:30 | Houston v South Florida | L | 54-42 |
| NCAAF | 2021/10/28 23:30 | South Florida v East Carolina | L | 14-29 |
| NCAAF | 2021/10/23 23:00 | Temple v South Florida | W | 14-34 |
| NCAAF | 2021/10/16 16:00 | Tulsa v South Florida | L | 32-31 |