[17] Reilly Opelka 6-1,6-4 Lorenzo Musetti [56] 2022-03-12 20:50
Stadium: Stadium 3 Round: 24 Ground: Hardcourt outdoor
Head to Head
| US Open | 2021/09/02 16:00 | Lorenzo Musetti v Reilly Opelka | 6-7,5-7,4-6 |
| ATP - Rom | 2021/05/11 11:10 | Lorenzo Musetti v Reilly Opelka | 4-6,4-6 |
Home History
| ATP - Delray Beach | 2022/02/20 20:00 | Cameron Norrie v Reilly Opelka | 7-6,7-6 |
| ATP - Delray Beach | 2022/02/20 01:00 | John Millman v Reilly Opelka | 6-7,7-6,6-7 |
| ATP - Delray Beach | 2022/02/18 23:00 | Adrian Mannarino v Reilly Opelka | 6-7,6-3,1-6 |
| ATP - Delray Beach | 2022/02/17 19:45 | Jack Sock v Reilly Opelka | 7-6,6-7,1-6 |
| ATP - Dallas | 2022/02/13 19:00 | Jenson Brooksby v Reilly Opelka | 6-7,6-7 |
| ATP - Dallas | 2022/02/12 22:00 | John Isner v Reilly Opelka | 6-7,6-7 |
| ATP - Dallas | 2022/02/12 02:25 | Adrian Mannarino v Reilly Opelka | 3-6,4-6 |
| ATP - Dallas | 2022/02/11 01:00 | Cedrik-Marcel Stebe v Reilly Opelka | 6-7,6-7 |
Away History
| ATP - Indian Wells | 2022/03/10 21:25 | Marcos Giron v Lorenzo Musetti | 3-6,5-7 |
| Davis Cup | 2022/03/05 18:30 | Norbert Gombos v Lorenzo Musetti | 7-6,2-6,4-6 |
| ATP - Dubai | 2022/02/21 18:15 | Novak Djokovic v Lorenzo Musetti | 6-3,6-3 |
| ATP - Rotterdam | 2022/02/11 12:00 | Lorenzo Musetti v Jiri Lehecka | 3-6,6-1,5-7 |
| ATP - Rotterdam | 2022/02/09 14:35 | Hubert Hurkacz v Lorenzo Musetti | 3-6,7-5,3-6 |
| ATP - Rotterdam | 2022/02/08 14:50 | Lorenzo Musetti v Mikael Ymer | 6-3,6-7,6-3 |
| ATP - Pune | 2022/02/04 07:30 | Kamil Majchrzak v Lorenzo Musetti | 6-2,6-7,6-4 |
| ATP - Pune | 2022/02/02 12:30 | Aleksandar Vukic v Lorenzo Musetti | 6-7,6-3,3-6 |