[27] Karen Khachanov 7-6,6-3 Mackenzie McDonald [51] 2022-02-14 16:15
Stadium: Centre Court Round: 25 Ground: Hardcourt outdoor
Head to Head
| Wimbledon | 2021/06/28 15:50 | Mackenzie McDonald v Karen Khachanov | 6-3,3-6,4-6,6-7 |
| ATP - Marseille | 2021/03/10 15:10 | Karen Khachanov v Mackenzie McDonald | 7-6,6-4 |
Home History
| ATP - Rotterdam | 2022/02/09 20:30 | Cameron Norrie v Karen Khachanov | 6-4,7-6 |
| ATP - Rotterdam | 2022/02/08 12:00 | Karen Khachanov v Alexei Popyrin | 6-7,6-1,7-6 |
| Australian Open | 2022/01/21 10:10 | Karen Khachanov v Rafael Nadal | 3-6,2-6,6-3,1-6 |
| Australian Open | 2022/01/19 07:30 | Karen Khachanov v Benjamin Bonzi | 6-4,6-0,7-5 |
| Australian Open | 2022/01/17 02:00 | Karen Khachanov v Denis Kudla | 3-6,6-3,6-2,7-6 |
| ATP - Adelaide 2 | 2022/01/13 00:30 | Karen Khachanov v Arthur Rinderknech | 6-7,5-7 |
| ATP - Adelaide 2 | 2022/01/12 03:35 | Karen Khachanov v Gianluca Mager | 7-5,6-3 |
| ATP - Adelaide | 2022/01/09 07:30 | Gaël Monfils v Karen Khachanov | 6-4,6-4 |
Away History
| ATP - Rotterdam | 2022/02/09 14:25 | Alex De Minaur v Mackenzie McDonald | 7-6,1-6,6-4 |
| ATP - Rotterdam | 2022/02/07 12:05 | Mackenzie McDonald v Nikoloz Basilashvili | 6-3,6-2 |
| ATP - Montpellier | 2022/02/03 18:30 | Alexander Zverev v Mackenzie McDonald | 6-2,7-6 |
| ATP - Montpellier | 2022/02/02 11:30 | Ilya Ivashka v Mackenzie McDonald | 3-6,6-7 |
| Australian Open | 2022/01/19 07:50 | Mackenzie McDonald v Aslan Karatsev | 6-3,2-6,2-6,3-6 |
| Australian Open | 2022/01/17 06:10 | Nikola Milojevic v Mackenzie McDonald | 7-5,4-6,3-6,2-6 |
| ATP - Adelaide 2 | 2022/01/10 07:45 | Mackenzie McDonald v Arthur Rinderknech | 3-6,7-6,3-6 |
| ATP - Melbourne | 2022/01/06 10:10 | Mackenzie McDonald v Botic Van De Zandschulp | 2-6,5-7 |