Stadium: Hart Recreation Center
Home Manager: Brett Nelson Away Manager: Carmen Maciariello
| USA - NCAAB | 2019/12/29 19:00 | Holy Cross v Siena | W | 62-74 |
| USA - NCAAB | 2018/12/22 17:05 | Siena v Holy Cross | L | 57-60 |
| USA - NCAAB | 2018/11/18 16:00 | Holy Cross v Siena | L | 57-45 |
| USA - NCAAB | 2017/12/23 00:00 | Siena v Holy Cross | W | 71-65 |
| USA - NCAAB | 2008/12/30 12:00 | Holy Cross v Siena | W | 71-83 |
| USA - NCAAB | 2007/12/22 12:00 | Siena v Holy Cross | W | 84-77 |
| USA - NCAAB | 2006/11/18 12:00 | Holy Cross v Siena | L | 65-57 |
| USA - NCAAB | 2005/12/01 12:00 | Siena v Holy Cross | W | 68-63 |
| USA - NCAAB | 2021/12/05 19:00 | Siena v St. Peter's | W | 60-58 |
| USA - NCAAB | 2021/12/04 00:00 | Manhattan v Siena | L | 77-72 |
| USA - NCAAB | 2021/12/01 00:00 | Siena v Army | W | 83-67 |
| USA - NCAAB | 2021/11/28 19:00 | Siena v Bucknell | L | 56-65 |
| USA - NCAAB | 2021/11/23 00:00 | Harvard v Siena | W | 69-72 |
| USA - NCAAB | 2021/11/19 23:30 | Siena v Georgetown | L | 65-83 |
| USA - NCAAB | 2021/11/17 00:00 | Yale v Siena | L | 82-54 |
| USA - NCAAB | 2021/11/14 00:00 | Delaware v Siena | L | 83-63 |
| USA - NCAAB | 2021/12/09 00:00 | Holy Cross v Fairfield | L | 59-74 |
| USA - NCAAB | 2021/12/04 19:00 | Holy Cross v La Salle | L | 65-84 |
| USA - NCAAB | 2021/12/02 00:00 | Holy Cross v Central Connecticut | L | 67-73 |
| USA - NCAAB | 2021/11/27 22:00 | New Hampshire v Holy Cross | L | 70-55 |
| USA - NCAAB | 2021/11/24 08:27 | Mount Saint Vincent v Holy Cross | W | 52-95 |
| USA - NCAAB | 2021/11/21 17:00 | Bryant v Holy Cross | L | 78-62 |
| USA - NCAAB | 2021/11/20 19:30 | Air Force v Holy Cross | L | 72-53 |
| USA - NCAAB | 2021/11/16 00:00 | Holy Cross v Quinnipiac | L | 68-76 |