Stadium: UTSA Convocation Center
Home Manager: Steve Henson Away Manager: Matt Crenshaw
| USA - NCAAB | 2021/11/16 23:00 | IUPUI v Texas A&M Corpus | L | 59-65 |
| USA - NCAAB | 2021/11/15 23:00 | IUPUI v Denver | L | 47-63 |
| USA - NCAAB | 2021/11/12 00:00 | IUPUI v Evansville | L | 40-60 |
| USA - NCAAB | 2021/11/09 23:45 | IUPUI v Butler | L | 47-56 |
| USA - NCAAB | 2021/02/26 01:00 | IUPUI v Wisc Milwaukee | L | 72-84 |
| USA - NCAAB | 2021/02/20 22:00 | IUPUI v Youngstown State | L | 70-77 |
| USA - NCAAB | 2021/02/19 22:00 | IUPUI v Youngstown State | W | 72-70 |
| USA - NCAAB | 2021/02/13 17:00 | Illinois-Chicago v IUPUI | W | 81-88 |
| USA - NCAAB | 2021/11/17 01:30 | Denver v Texas San Antonio | W | 64-78 |
| USA - NCAAB | 2021/11/16 00:30 | Texas San Antonio v Texas A&M Commerce | L | 62-65 |
| USA - NCAAB | 2021/11/13 01:00 | Texas San Antonio v Oklahoma | L | 44-96 |
| USA - NCAAB | 2021/11/10 01:30 | Texas San Antonio v Trinity | W | 97-66 |
| USA - NCAAB | 2021/03/11 23:30 | Texas San Antonio v Western Kentucky | L | 67-80 |
| USA - NCAAB | 2021/03/10 23:30 | Charlotte U v Texas San Antonio | W | 62-72 |
| USA - NCAAB | 2021/02/27 21:00 | Texas San Antonio v UAB | W | 96-79 |
| USA - NCAAB | 2021/02/27 00:00 | UAB v Texas San Antonio | L | 64-57 |