Florida Intl 17-37 Southern Mississippi 2021-11-27 20:00
Stadium: M.M. Roberts Stadium Round: 1
Home Manager: Will Hall Away Manager: Butch Davis
Home History
| NCAAF | 2021/11/21 00:00 | North Texas v Florida Intl | L | 49-7 |
| NCAAF | 2021/11/13 20:30 | Florida Intl v Middle Tennessee St. | L | 10-50 |
| NCAAF | 2021/11/06 23:00 | Old Dominion v Florida Intl | L | 47-24 |
| NCAAF | 2021/10/30 19:30 | Florida Intl v Marshall | L | 0-38 |
| NCAAF | 2021/10/23 23:00 | Western Kentucky v Florida Intl | L | 34-19 |
| NCAAF | 2021/10/08 23:00 | Charlotte v Florida Intl | L | 45-33 |
| NCAAF | 2021/10/02 19:30 | Florida Intl v Florida Atlantic | L | 21-58 |
| NCAAF | 2021/09/25 16:00 | Florida Intl v Central Michigan | L | 27-31 |
Away History
| NCAAF | 2021/11/20 01:00 | Southern Mississippi v Louisiana Tech | W | 35-19 |
| NCAAF | 2021/11/13 20:30 | Southern Mississippi v Texas-San Antonio | L | 17-27 |
| NCAAF | 2021/11/06 19:00 | North Texas v Southern Mississippi | L | 38-14 |
| NCAAF | 2021/10/30 19:30 | Southern Mississippi v Middle Tennessee St. | L | 10-35 |
| NCAAF | 2021/10/16 19:30 | UAB v Southern Mississippi | L | 34-0 |
| NCAAF | 2021/10/09 23:00 | UTEP v Southern Mississippi | L | 26-13 |
| NCAAF | 2021/10/02 22:30 | Southern Mississippi v Rice | L | 19-24 |
| NCAAF | 2021/09/25 23:30 | Southern Mississippi v Alabama | L | 14-63 |