[3] Lokomotiv Moskva 1-2 Rostov [16] 2021-10-03 16:00
Stadium: RZD Arena Round: 10
Referee: Pavel Kukuyan Home Manager: Marko Nikolic Away Manager: Yury Semin
Head to Head
| Europa - Venskabskampe | 2021/07/12 09:00 | Rostov v Lokomotiv Moskva | L | 2-1 |
| Rusland - Premier League | 2021/04/17 13:30 | Lokomotiv Moskva v Rostov | W | 4-1 |
| Europa - Venskabskampe | 2021/02/14 14:34 | Lokomotiv Moskva v Rostov | W | 2-1 |
| Rusland - Premier League | 2020/09/14 17:30 | Rostov v Lokomotiv Moskva | D | 0-0 |
| Rusland - Premier League | 2020/03/15 16:00 | Rostov v Lokomotiv Moskva | W | 1-3 |
| Europa - Venskabskampe | 2020/02/09 15:00 | Rostov v Lokomotiv Moskva | W | 7-8 |
| Rusland - Premier League | 2019/08/31 13:30 | Lokomotiv Moskva v Rostov | L | 1-2 |
| Rusland - Pokal | 2019/05/15 16:30 | Rostov v Lokomotiv Moskva | W | 0-2 |
Home History
| UEFA Europa League | 2021/09/30 19:00 | Lazio v Lokomotiv Moskva | L | 2-0 |
| Rusland - Premier League | 2021/09/25 11:00 | FK Khimki v Lokomotiv Moskva | D | 0-0 |
| Rusland - Premier League | 2021/09/20 13:30 | Ural v Lokomotiv Moskva | D | 0-0 |
| UEFA Europa League | 2021/09/16 16:45 | Lokomotiv Moskva v Marseille | D | 1-1 |
| Rusland - Premier League | 2021/09/11 11:00 | Lokomotiv Moskva v Krylya Sovetov | W | 2-0 |
| Europa - Venskabskampe | 2021/09/05 14:00 | CSKA Moskva v Lokomotiv Moskva | W | 1-2 |
| Rusland - Premier League | 2021/08/27 16:00 | Dinamo Moskva v Lokomotiv Moskva | D | 1-1 |
| Rusland - Premier League | 2021/08/22 13:00 | Lokomotiv Moskva v Krasnodar | W | 2-1 |
Away History
| Rusland - Premier League | 2021/09/26 13:30 | Rostov v FC Akhmat Grozny | L | 1-2 |
| Rusland - Pokal | 2021/09/22 16:30 | Rostov v Chaika Petropavlovskaya | L | 0-1 |
| Rusland - Premier League | 2021/09/18 13:30 | Krylya Sovetov v Rostov | L | 4-2 |
| Rusland - Premier League | 2021/09/13 16:30 | Rostov v Krasnodar | D | 1-1 |
| Rusland - Premier League | 2021/08/27 13:30 | Ural v Rostov | D | 1-1 |
| Rusland - Premier League | 2021/08/22 15:00 | FC Nizhny Novgorod v Rostov | W | 1-2 |
| Rusland - Premier League | 2021/08/14 17:00 | Rostov v CSKA Moskva | L | 1-3 |
| Rusland - Premier League | 2021/08/08 14:30 | FK Khimki v Rostov | D | 1-1 |