[101] South Florida 21-56 Houston [82] 2020-11-14 20:30
Stadium: John O'Quinn Field at TDECU Stadium Round: 1
Head to Head
| NCAAF | 2018/10/27 19:30 | South Florida v Houston | L | 36-57 |
| NCAAF | 2017/10/28 19:45 | Houston v South Florida | L | 28-24 |
| NCAAF | 2014/11/01 20:00 | South Florida v Houston | L | 3-27 |
| NCAAF | 2002/11/23 12:00 | Houston v South Florida | W | 14-32 |
| NCAAF | 2001/11/03 12:00 | South Florida v Houston | W | 45-6 |
Home History
| NCAAF | 2020/11/07 17:00 | South Florida v Memphis | L | 33-34 |
| NCAAF | 2020/10/23 23:30 | Tulsa v South Florida | L | 42-13 |
| NCAAF | 2020/10/17 16:00 | South Florida v Temple | L | 37-39 |
| NCAAF | 2020/10/10 23:00 | East Carolina v South Florida | L | 44-24 |
| NCAAF | 2020/10/03 19:30 | South Florida v Cincinnati | L | 7-28 |
| NCAAF | 2020/09/19 18:30 | South Florida v Notre Dame | L | 0-52 |
| NCAAF | 2020/09/12 23:00 | The Citadel v South Florida | W | 6-27 |
| NCAAF | 2019/11/30 01:00 | South Florida v Central Florida | L | 7-34 |
Away History
| NCAAF | 2020/11/07 20:30 | Houston v Cincinnati | L | 10-38 |
| NCAAF | 2020/10/31 18:00 | Central Florida v Houston | L | 44-21 |
| NCAAF | 2020/10/24 19:30 | Houston v Navy | W | 37-21 |
| NCAAF | 2020/10/17 01:30 | BYU v Houston | L | 43-26 |
| NCAAF | 2020/10/08 23:30 | Tulane v Houston | W | 31-49 |
| NCAAF | 2019/12/01 00:00 | Navy v Houston | L | 56-41 |
| NCAAF | 2019/11/24 00:30 | Houston v Tulsa | W | 24-14 |
| NCAAF | 2019/11/16 20:30 | Memphis v Houston | L | 45-27 |