Stadium: Cowboy Stadium Round: 1
Home Manager: Sterlin Gilbert Away Manager: Dawson Odums
| NCAAF | 2018/12/01 21:30 | Southern v Alcorn State | L | 28-37 |
| NCAAF FCS | 2018/11/24 22:00 | Grambling State v Southern | W | 28-38 |
| NCAAF FCS | 2018/11/10 22:00 | Arkansas Pine Bluff v Southern | W | 24-56 |
| NCAAF | 2018/10/27 23:00 | Southern v Jackson State | W | 41-7 |
| NCAAF | 2018/10/20 19:00 | Texas Southern Tigers v Southern | W | 7-21 |
| NCAAF | 2018/10/13 22:00 | Southern v Prairie View | W | 38-0 |
| NCAAF | 2018/09/29 23:00 | Alcorn State v Southern | L | 20-3 |
| NCAAF | 2018/09/22 21:00 | Alabama v Southern | W | 27-29 |
| NCAAF FCS | 2018/11/17 21:00 | Lamar v McNeese State | L | 21-17 |
| NCAAF FCS | 2018/11/11 00:00 | McNeese State v Northwestern State | L | 34-37 |
| NCAAF FCS | 2018/11/03 19:30 | McNeese State v SE Louisiana | L | 6-23 |
| NCAAF | 2018/10/27 23:00 | McNeese State v Central Arkansas | W | 23-21 |
| NCAAF | 2018/10/20 21:00 | McNeese State v Incarnate Word | L | 17-45 |
| NCAAF | 2018/10/06 23:00 | Abilene Christian v McNeese State | W | 21-24 |
| NCAAF | 2018/09/29 23:00 | Stephen F. Austin v McNeese State | W | 10-17 |
| NCAAF | 2018/09/22 22:00 | McNeese State v BYU | L | 3-30 |